Category: Research Briefs
Ketogenic-Diet Responses Varied by Weight and Sex in 60-Day Study
A 60-day single-arm study found varied glucose, insulin, lipid, hormone, and body-composition responses to a ketogenic diet.
Brief High-Fat Feeding Left an Inflammatory Memory—in Mice
Mouse experiments found that high-fat feeding around an initial inflammatory episode amplified later local immune responses.
MIND Diet Adherence Was Linked to Slightly Slower Biological Aging
A 1,740-person observational preprint linked stronger MIND-diet adherence with modestly younger DNA-based aging measures three years later.
Heart-Risk Warning Signs Can Appear Before Diabetes Is Diagnosed
A 42,907-person observational study found unfavorable triglyceride-to-HDL ratios and rising blood pressure before diabetes diagnosis, highlighting heart risk beyond glucose.
Gut Bacteria May Help the Body Tell When Food Arrives
A new mouse and laboratory study explains how a common gut bacterium may connect food timing with nutrient absorption. Human benefits remain unproven.
Ultra-Processed Foods Were Not All Alike in Colorectal-Cancer Study
A 461,682-person cohort found no overall colorectal-cancer link for total ultra-processed food intake, but associations differed by food type.
SGLT2 Drugs Reduced Heart-Failure and Kidney Events Across 14 Diabetes Trials
A meta-analysis of 14 placebo-controlled trials found lower relative risks of heart-failure hospitalization, cardiovascular death, and composite kidney outcomes with SGLT2 inhibitors in adults with type 2 diabetes.
Brown Fat Looked Promising—but Losartan Evidence Is Not Yet Human
A large retrospective imaging study linked greater brown-fat activity with favorable cardiometabolic patterns, while losartan activated brown fat only in cell and mouse experiments.
Continuous Glucose Monitoring Lowered HbA1c Without Insulin in a 283-Person Trial
A 26-week randomized trial found that continuous glucose monitoring improved HbA1c and time in range among adults with type 2 diabetes who were not using insulin.
Higher Paternal BMI Was Linked to Sperm DNA Methylation Differences
A human observational study links paternal BMI and age with sperm DNA methylation patterns, without proving effects on children.
Three Lab Values Were Linked to Mortality Risk—but the Score Is Not Yet Ready for Clinical Use
A large U.S. observational study linked the EASIX laboratory score with mortality, but it has not been validated for routine CKM risk screening.
Coffee Stayed Steady—but Creamer Added More Calories
A national analysis found stable coffee intake but rising calories from add-ins, led by non-dairy creamer.