Deadline passes without word from Senate hopeful Akin

WASHINGTON (Reuters) – A deadline passed on Tuesday evening with no indication from Republican U.S. Representative Todd Akin that he would bow to party pressure and quit the Missouri Senate race over his controversial remarks on abortion and rape. Missouri election law gave Akin until 5 p.m. local time (6 p.m. EDT) to take himself off the November 6 ballot in the Senate race against Democrat Claire McCaskill. Party leaders including Republican presidential hopeful Mitt Romney and Senate Republican leader Mitch McConnell had strongly urged him to step down. …

AstraZeneca sales hit hard by generic competition

LONDON (Reuters) – AstraZeneca’s sales tumbled 21 percent in the second quarter, punished by generic competition to its best-selling antipsychotic medicine Seroquel and pressure on health spending in Europe. Continued supply chain disruptions triggered by problems with a new IT system at a plant in Sweden added to the group’s woes and the shares fell 1.8 percent by 04.30 a.m. EDT in a flat market for European drug stocks. …