Scientists hail breakthrough in embryonic-like stem cells

By Kate Kelland, Health and Science Correspondent LONDON (Reuters) – In experiments that could open a new era in stem cell biology, scientists have found a simple way to reprogram mature animal cells back into an embryonic-like state that allows them to generate many types of tissue. Chris Mason, chair of regenerative medicine bioprocessing at University College London, who was not involved in the work, said its approach in mice was “the most simple, lowest-cost and quickest method” to generate so-called pluripotent cells – able to develop into many different cell types – from mature cells. The researchers took skin and blood cells, let them multiply, then subjected them to stress “almost to the point of death”, they explained, by exposing them to various events including trauma, low oxygen levels and acidic environments. Within days, the scientists found that the cells had not only survived but had also recovered by naturally reverting into a state similar to that of an embryonic stem cell.