FDA warns against use of Pfizer’s Revatio in children

(Reuters) – U.S. health regulators recommended against use of Pfizer Inc’s pulmonary arterial hypertension (PAH) drug Revatio in children up to 17 years of age, saying it had a higher risk of death when taken in a high dose. While the drug has never been approved for treatment of PAH in children, the U.S. Food and Drug Administration’s warning is against off-label use of the drug. …