FDA advisers recommend approval of Titan Pharma’s opioid dependence drug

By Zeba Siddiqui (Reuters) – Advisers to the U.S. Food and Drug Administration recommended that Titan Pharmaceuticals Inc treatment for opioid addiction be approved, but were unconvinced that the company’s marketing plan was safe enough, given the potential for abuse of such drugs. The panel of advisers, who met in Silver Spring, Maryland to evaluate the safety and efficacy of Titan’s Probuphine, also echoed concerns expressed on Tuesday by FDA staff, who said it was difficult to decide if the intended dose of the drug would be effective enough. …