USAID: Eyes on Guinea as Liberia, Sierra Leone improve on Ebola

A health worker escorts a newly admitted Ebola patient in to the Kerry town Ebola treatment centre outside FreetownWASHINGTON (Reuters) – The rate of new Ebola cases in Liberia has plunged, Sierra Leone is beginning to turn the corner in dealing with the deadly virus and health officials are now focused on Guinea, a USAID official said on Tuesday. Guinea is "where we have our eye on at the moment," said Jeremy Konyndyk, director of the USAID office of U.S. Foreign Disaster Assistance. He said the rate of new cases in Liberia have dropped from more than 30 a day to single digits. Health officials cautioned that there is still a long way to go to eradicate the disease.

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Slowdown, U.S. problems prompt Philips profit warning

A Philips logo is seen at Philips headquarters in AmsterdamBy Toby Sterling AMSTERDAM (Reuters) – Philips warned on Tuesday that fourth-quarter earnings would be worse than expected because of the lengthy closure of a manufacturing plant in Cleveland, Ohio and a slowdown in some of its major markets. The latest profit warning from the Dutch industrial company comes after its stock underperformed benchmarks and Chief Executive Frans van Houten announced plans last year to break up the company, splitting off its lighting business. …

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Lilly to test combinations with Merck, Bristol-Myers’ cancer drugs

(Reuters) – Eli Lilly & Co signed two separate deals with Merck & Co Inc and Bristol-Myers Squibb Co to test combinations of its cancer treatments with two recently approved therapies that belong to a promising new class of drugs. Lilly will test its treatments – approved and experimental – in combination with PD-1 inhibitors Keytruda and Opdivo. The treatments are designed to help the body’s own immune system fight cancer by blocking a protein called Programmed Death receptor (PD-1). Bristol-Myers’ Opdivo was approved by the U.S. Food and Drugs Administration on Dec. 22. …
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FDA seeks more safety data on Antares testosterone drug

A view shows the U.S. Food and Drug Administration (FDA) headquarters in Silver Spring(Reuters) – Antares Pharma Inc said the U.S. Food and Drug Administration has asked for additional safety data on its testosterone drug after a patient developed hives in a mid-stage trial. Antares' shares fell 7.6 pct in premarket trading on Tuesday on concerns that the regulator's request could delay the company's marketing application for the drug. The FDA has become more cautious about approving testosterone drugs after it found late last year that more than a fifth of the patients prescribed such drugs did not get their testosterone levels tested before or during treatment. …

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