GSK cancer vaccine fails again but testing continues

A no entry sign is pictured outside the GlaxoSmithKline building in Hounslow, west LondonAn experimental cancer vaccine from GlaxoSmithKline has failed in a second test – this time against lung cancer – but the British company said it still hoped to identify a sub-group of patients in which it would work. Thursday's news that the MAGE-A3 therapeutic vaccine did not help patients with non-small cell lung cancer in a late-stage study is a further blow to the high-risk, high-reward project after a similar setback in melanoma in September. The large Phase III study, involving more than 2,000 lung cancer patients, found that the experimental therapy did not help patients live longer without their disease recurring. Vincent Brichard, head of immunotherapeutics at GSK Vaccines, said the company was disappointed by the outcome but remained committed to the project.

6 Signs Your Diet Is Too Extreme

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A Minute With: John Caird melds Ugandan dance, Japanese drums, U.S. chorus

By Elaine Lies TOKYO (Reuters) – Samurai, Ugandan dance, a U.S. chorus and the thunder of traditional Japanese taiko drums mix and meld in a cross-cultural charity collaboration to raise money for orphans around the world. “At Home in the World”, performed by Ugandan youth whose parents died from HIV/AIDS and Japanese young people who lost loved ones in the 2011 tsunami, as well as a chorus from Vassar College in the United States, is directed by award-winning Briton John Caird and was playing in Tokyo on Thursday. A: The difficult thing was teaching Ugandan children to sing in Western tonality because they do tribal shout singing, which doesn’t actually land on any key… But I suppose a bigger challenge was getting the Vassar students to behave like samurai. At first, the Vassar students were walking across the stage like big bags of dough.

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