Merck’s insomnia drug moves a step closer to U.S. approval

A view of the Merck & Co. campus in Linden, New JerseyBy Toni Clarke WASHINGTON (Reuters) – Merck & Co's experimental insomnia drug moved a step closer to U.S. approval on Wednesday after a panel of medical experts said it is effective and safe at lower doses. The advisory panel was convened to help the U.S. Food and Drug Administration decide whether to approve the drug, suvorexant, which would be the first in a new class of sedatives that block chemicals in the brain called orexins that help keep people awake. The drugs are designed to help people fall asleep and stay asleep. …

Senate committee advances drug compounding bill

By Jessica Dye NEW YORK (Reuters) – A U.S. Senate committee on Wednesday unanimously approved legislation that would increase federal oversight for companies that compound and sell sterile drugs across state lines. The proposed legislation was introduced in response to a meningitis outbreak last fall that killed more than 50 people and sickened more than 700. The outbreak was traced to contamination found in steroid injections made by the New England Compounding Center. The bill was passed unanimously on a voice vote by the Senate Health, Education, Labor and Pension Committee. …

FDA panel says Merck’s sleep drug safe, effective at lower dose

A view of the Merck & Co. campus in Linden, New JerseyBy Toni Clarke WASHINGTON (Reuters) – Merck & Co's experimental insomnia drug was safe and effective at the lower of two doses studied, a panel of medical experts said on Wednesday, increasing the chance it will be approved by the U.S. Food and Drug Administration. The advisory panel was convened to help the FDA decide whether to approve the drug, suvorexant, which would be the first in a new class of sedatives designed to help people fall asleep and stay asleep. …

Health officials probe deadly respiratory illness in Alabama

By Verna Gates BIRMINGHAM, Alabama (Reuters) – U.S. and state health authorities are investigating an unidentified respiratory illness that has killed two of 10 people hospitalized with it in Alabama since last week. Preliminary tests do not indicate the bird flu, nor a new mutation of any known influenza virus, said Dr. Mary McIntyre, an assistant state health officer at the Alabama Department of Public Health. Two patients did test positive for the H1N1 strain of the flu. …

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