Lilly stops rheumatoid arthritis trial for lack of efficacy

(Reuters) – Eli Lilly and Co said it will stop one of three late-stage trials of its rheumatoid arthritis drug tabalumab after an analysis showed that the trial was unlikely to be successful. The trial was testing the drug in patients with moderate-to-severe rheumatoid arthritis who were not responding adequately to methotrexate therapy, which is a standard rheumatoid arthritis treatment. The decision was not based on safety concerns, and patients currently enrolled in other tabalumab rheumatoid arthritis studies will continue treatment, Lilly said. …

Senate leader says Boehner should yield to public on tax hikes

WASHINGTON, Dec 13 – The top Republican in Congress should yield to public opinion and permit an increase in tax rates on the wealthiest Americans, Senate Democratic Leader Harry Reid said on Thursday. House of Representatives Speaker John Boehner “can’t ignore the American people forever,” Reid told a Capitol Hill news conference. He cited polls showing that most Americans favor raising taxes on the rich while extending tax cuts for the middle class as part of a possible deal to avert “the fiscal cliff,” automatic tax hikes and budget cuts set to begin in 2013. …

Aerobic exercise boosts brain power, review finds

The physical benefits of regular exercise and remaining physically active, especially as we age, are well documented. However, it appears that it is not only the body which benefits from exercise, but the mind too. The evidence for this is published in a new review that focuses on the importance of physical activity in keeping and potentially improving cognitive function throughout life.

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