FDA advisers back NPS’s drug for short bowel syndrome

(Reuters) – U.S. drug advisers on Tuesday backed a drug to treat a rare and serious bowel disorder for which there is no long-term treatment available in the United States. A panel of outside advisers to the U.S. Food and Drug Administration agreed that NPS Pharmaceuticals Inc had demonstrated that the drug is safe and improves absorption of fluid and nutrients in the intestines of adults with short bowel syndrome. The 12-member panel voted unanimously in the drug’s favor. The FDA usually follows the advice of expert panels. …

Early muscle training linked to lower knee risk for girls

NEW YORK (Reuters Health) – Exercises aimed at preventing knee injuries in athletes are most effective when they’re started young, according to a new analysis of clinical trial results. The new study, published in the American Journal of Sports Medicine, looked at more than a dozen other studies and found that female athletes who started so-called neuromuscular training routines by about age 14 were 72 percent less likely to hurt their knee ligaments than those who did not get the training until they were college-age. …

Cholesterol levels declining in U.S

NEW YORK (Reuters Health) – The cholesterol levels of U.S. adults have been dropping since the late 1980’s, a new study suggests – and not just because of the increased popularity of lipid-lowering drugs. Researchers said that cholesterol, which is closely tied to heart disease risk, may be looking better because of improvements in diet, including the substitution of vegetable oils for less-healthy trans fats. They found average total cholesterol dropped from 206 milligrams per deciliter in 1988-1994 to 196 in 2007-2010, with a similar decrease in “bad” LDL cholesterol. …

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