Scientists see mechanism for spontaneous HIV ‘cure’

French scientists have unveiled the genetic mechanism by which they believe two men were cured of HIVFrench scientists said Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS. Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms. The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said. HIV replicates by invading human CD4 immune cells, which it reprogrammes to become virus factories.

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Singapore clamps down on shisha smoking

A customer smokes a shisha pipe at a cafe in Singapore, on November 4, 2014The Singapore government said Tuesday it would phase out public shisha smoking to protect young people who feel that smoking tobacco through water pipes is less harmful than cigarettes. Faishal Ibrahim, parliamentary secretary for the health ministry, told a legislative session that a ban on new licences for shisha imports and sales would come into force this month. "In view of the health risks associated with shisha smoking and to prevent the proliferation and entrenchment of shisha smoking in Singapore, my ministry intends to prohibit the import, distribution and sale of shisha," Faishal told lawmakers. The minimum age for smoking in Singapore, including at shisha bars and cafes, is 18.

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Regeneron cuts top end of eye drug sales forecast

(Reuters) – Regeneron Pharmaceuticals Inc cut the top end of its full-year sales forecast for its blockbuster eye drug and reported a lower-than-expected adjusted quarterly profit, citing higher costs. The company’s shares fell 7.6 percent to $365 in premarket trading on Tuesday. Regeneron said it expected full-year 2014 sales of Eylea, its eye injection drug, within a range of $1.7 billion to $1.74 billion. The company, more accustomed to raising its Eylea sales forecasts, cut the range from $1.7 billion to $1.8 billion. …
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Legal marijuana gets major test in Oregon, Alaska, and D.C. ballots

Canvasser leaves campaign literature to drum up support for Oregon's Measure 91, which would legalize the recreational use of marijuana in Portland, OregonBallot measures in Oregon and Alaska would set up a network of regulated pot shops, similar to those already operating in Colorado and Washington state after twin landmark votes in 2012. The referendums come amid rapid shifts in Americans' opinions on marijuana in recent years that have seen efforts to legalize cannabis creep closer toward the mainstream and brought about sweeping pot policy changes in states and cities, where the drug remains illegal under federal law. "Win or lose, we expect to see more support and more dialogue about the issue than ever," said Mason Tvert, a spokesman for the Marijuana Policy Project, which is working on legalization measures in California and other states for 2016.

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Diabetes care, drug-delivery power Becton Dickinson’s beat

(Reuters) – Medical equipment maker Becton Dickinson & Co reported better-than-expected profit and revenue, helped by strong sales in its diabetes care and drug-delivery businesses. Becton said it expected adjusted earnings from continuing operations to be between $6.76 and $6.83 per share for the year ending September 2015. Analysts on average were expecting $6.70 per share, according to Thomson Reuters I/B/E/S. …
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